94 research outputs found
Bioavailability of iodine from a meal consisting of sushi and a wakame seaweed salad—A randomized crossover trial
The consumption of seaweed is on the rise in the Western world. Seaweeds may contain substantial amounts of iodine, and some species could serve as a potential dietary iodine source. However, limited data on the iodine content and in vivo bioavailability of iodine from seaweeds exist. The objective was to assess whether iodine from a meal consisting of sushi with nori, (Porphyra spp) and a wakame seaweed salad (Undaria pinnatifida) had similar bioavailability as a potassium iodide reference supplement of similar iodine content. A randomized 2 × 2 crossover trial (AB/BA model) was conducted in 20 healthy young women. One intervention arm consisted of a meal with sushi and wakame salad (231 μg iodine), and the other of potassium iodide (KI) supplement (225 μg iodine). Urinary iodine concentration (UIC) was measured at 11 different time points for 48 h after the interventions. The UIC increased after consumption of both the sushi and wakame meal and the KI supplement, but the median UIC was higher after ingestion of the KI supplement. The estimated bioavailability of iodine during the first 24 h was 75% from sushi with wakame and 97% from the KI supplement. The bioequivalence analyses confirmed that the KI supplement had higher estimated bioavailability than the sushi and wakame meal, however, with small margins. Our findings on iodine bioavailability imply that sushi and wakame could be potential iodine sources in the diet, which may be favorable for population groups at risk for iodine deficiency. However, further research is needed to account for the variability of iodine content in seaweeds by different locations and degree of processing, to assure that the iodine levels are stable and predictable for the consumers.Bioavailability of iodine from a meal consisting of sushi and a wakame seaweed salad—A randomized crossover trialpublishedVersio
Associations between thyroid dysfunction and developmental status in children with excessive iodine status
Background and objective: Adequate iodine status and normal thyroid hormone synthesis are important for optimal child development. In this study, we explored whether young children’s developmental status is associated with thyroid dysfunction in an area of chronic excessive iodine exposure. Methods: We included 298 children between 18 and 48 months of age residing in Algerian refugee camps. Early child development was measured using the Ages and Stages Questionnaires, third edition (ASQ-3), consisting of five domains: Communication, Gross Motor, Fine Motor, Problem Solving and Personal-Social. Due to poor discriminatory ability in the Gross Motor domain, the total ASQ-3 scores were calculated both including and excluding this domain. Urinary iodine concentration (UIC), thyroid hormones (TSH, FT3 and FT4), thyroid antibodies and serum thyroglobulin (Tg) were measured. Results: The median UIC was 451.6 μg/L, and approximately 72% of the children had a UIC above 300 μg/L. Furthermore, 14% had thyroid disturbances, of whom 10% had TSH outside the reference range. Children with thyroid disturbances and TSH outside the reference ranges had lower odds of being among the 66% highest total ASQ scores, with adjusted odds ratios (95% CI) of 0.46 (0.23, 0.93) and 0.42 (0.19, 0.94), respectively. Conclusion: We found an association between thyroid dysfunction and poorer developmental status among children with excessive iodine intake. The high iodine intake may have caused the thyroid dysfunction and hence the delayed developmental status; however, other influential factors cannot be excluded. Optimal child development is important for a sustainable future. With iodine excess being an increasing problem globally, this subject should be further explored.publishedVersio
High iodine content in local animal milk and risk of exceeding EFSA upper intake level for iodine among Saharawi women
Excessive iodine intake is a major public health problem in the Saharawi refugee camps in Algeria, where animal milk is an important source of iodine. The purpose of this study was to assess the association between iodine concentrations in locally produced animal milk and in animal drinking water and further to assess the risk of exceeding European Food Safety Authority (EFSA) tolerable upper intake level for iodine (600 μg/d) among Saharawi women. In 2009 and 2010, 202 milk samples from goats and sheep and 52 milk samples from camel were collected. Iodine in milk was determined by Inductively Coupled Plasma-Mass Spectrometry (ICP-MS). In addition, iodine in 56 water samples from the general water system and 54 water samples from wells, was determined by modified Sandell-Kolthoff reaction. Animal milk is generally consumed mixed with water. The median (min, max) iodine intake from goat/sheep milk mixed with water in camps with high iodine content in human drinking water was 284 (57, 2889) μg/d and 19% of participants exceeded EFSA upper intake level for iodine. The median (min, max) iodine intake from camel milk mixed with water in all camps was 2100 (210, 11100) and 47% of participants exceeded the EFSA upper intake level. The median (min, max) iodine content in goat/sheep milk from camps with moderate and high iodine content in water was 507 (101, 4791) μg/L and 1612 (487, 9323) μg/L, respectively (p < 0.001). The iodine content in goat/sheep milk was positively associated with iodine content in animal drinking water (regression coefficient, B 5.71, 95% CI 4.03, 7.39). In conclusion, consumption of camel milk and living in camps with high water iodine content increased the risk of exceeding the EFSA upper intake level for iodine. We suggest that purified water for both human and animal consumption should be provided.publishedVersio
Brannslukker i et hav med oppgaver - om avdelingslederens mange oppgaver i grunnskolen
Vi har i denne oppgaven studert avdelingslederrollen til Bergen kommune på
ungdomsskolenivå. Vi har tatt utgangspunkt i hva kommunen gjennom det som ble besluttet i
2010 har bestemt at avdelingsleder skal ha som arbeidsoppgaver, og sett på hva de i
virkeligheten gjør.
Undersøkelsen vår har vært gjennomført som en kvalitativ studie der vi har intervjuet 13
skoleledere ved fire ulike ungdomsskoler. To av skolene har vært “rene” ungdomsskoler,
mens to av skolene har vært kombinertskoler med både barne-og ungdomstrinn. I tillegg
valgte vi ut at to av skolene skulle ha egen rådgiverstilling, mens to av skolene hadde denne
funksjonen som en del av avdelingslederstillingen. På alle fire skolene deltok både rektor og
alle avdelingslederne i intervjurunden.
Vi har i våre funn avdekket at det er et sprik mellom forventningene Bergen kommune har til
hva avdelingslederne skal arbeide med på skolen, og hva de faktisk gjør. Avdelingslederne på
skolene vi har undersøkt bruker mindre tid enn ønsket på pedagogisk utviklingsarbeid.
Elevsaker og driftssaker blir prioritert foran pedagogisk utviklingsarbeid, dette er også noe
rektorene anerkjenner. Elevsaker tar mye av tiden til avdelingslederne og det noe som har
vært økende de siste årene. Selv om noen av skolene har egne rådgivere og miljøveiledere,
ser ikke dette ut til å redusere arbeidsmengden til avdelingslederne knyttet til elevsaker.
Avdelingslederne i Bergen kommune skal ha minimum 30% undervisning i sin stilling, for å
redusere avstanden mellom lærerne og ledelsen, samtidig som en skal være tett på
klasseromspraksis. På skolene vi har undersøkt, har alle avdelingslederne mindre enn 30%
undervisning. Dette begrunnes med deltakelse i møter og andre prioriteringer som gjør at det
vanskelig å følge opp undervisning som ligger på faste tidspunkt. Total arbeidsmengde er
også noe som gjør at undervisning blir nedprioritert. Avdelingsledere på 3 av 4 skoler sier at
de jobber utover arbeidstiden, noe av dette er forventet og de får 10 dager til avspasering,
men dette ser ikke ut til å være dekkende for arbeidsmengden som blir beskrevet av våre
respondenter. På to av skolene har avdelingslederne ansvar for vikarer i perioder, noe som
også øker arbeidsmengden og belastningen for avdelingslederne.
Vi mener at våre funn bør være interessante både for rektor som enhetsleder og Bergen
kommune som skoleeier i et videre arbeid med avdelingslederrollen.nhhma
Putting small fish on the table: the underutilized potential of small indigenous fish to improve food and nutrition security in East Africa
Sub-Saharan Africa has a high prevalence of food insecurity. Small pelagic fish such as Silver cyprinid (Rastrineobola argentea) which is indigenous to Lake Victoria, can be a nutritious animal sourced food that contributes to a more nutrient dense diet. Potential sustainable catch of Silver cyprinid is estimated at 2 million tonnes yearly, which is four times the amount of the current catch. Whole sun-dried Silver cyprinid was purchased from several markets in Kenya and analysed for nutrient composition, microbial counts and metal content. The results show that utilizing the whole potential catch of Silver cyprinid would provide a significant daily source of vitamin B12, calcium, zinc and iron to the roughly 33 million people living in the Lake Victoria basin. Heavy metal concentration appears to be low, but other food safety aspects like microbial counts call for value chain improvements. We conclude that the underutilized potential of sun-dried Silver cyprinid could substantially contribute to fight malnutrition and food insecurity by providing an affordable nutrient dense animal sourced food to a large number of people. It also highlights the need to improve the value chains to increase the safety of these products.publishedVersio
Variation in Nutrient Composition of Seafood from North West Africa: Implications for Food and Nutrition Security
publishedVersio
Validation and reproducibility of a new iodine specific food frequency questionnaire for assessing iodine intake in Norwegian pregnant women
Iodized salt is not mandatory in Norway, and the permitted level of iodine in table salt is low (5 μg/g). Thus, milk and dairy products, fish and eggs are the main dietary sources of iodine in Norway. Mild-to-moderate iodine deficiency in pregnant women has been described in several European countries, including Norway. There are few validated tools available to assess iodine intake in an efficient manner. The aim of the current study was to assess the validity and reproducibility of a new iodine-specific food frequency questionnaire (I-FFQ) in Norwegian pregnant women.publishedVersio
Comparison of a digital iodine-specific dietary screener with 24-hour recall and urinary iodine concentration
Mild-to-moderate iodine deficiency remains a problem worldwide, including in Norway. Of particular, concern is fertile, pregnant and lactating women. The Norwegian Dairy Council developed a digital iodine-specific dietary screener (I-screener) for the assessment of iodine intake levels but has yet to be validated. The aim was thus to investigate the relative validity of the I-screener by comparing estimates of iodine intake from the I-screener against a single 24-hour recall (24HR) and urinary iodine concentration (UIC) in fertile women. Healthy females were recruited in Bergen in August–December 2021. Six spot-urine samples from six consecutive days were collected into a pooled sample to assess UIC. Each participant completed a single administration of the I-screener and the 24HR. The estimated daily iodine intake from the I-screener was compared with the estimations from the 24HR and UIC. Seventy-two women aged 19–39 completed the study. The median UIC was 76 μg/l. Compared with the 24HR, the I-screener placed 83 % of the participants in the same/adjacent tertial, with a slight agreement between the methods (Cohen's kappa = 0⋅187). The present study shows an acceptable correlation between the I-screener and the 24HR (r = 0⋅318), but not between the I-screener and UIC (r = 0⋅122). Despite its varying iodine estimate abilities, the I-screener may be used as an initial screening tool to rank fertile women on an individual level into deficient inadequate, and sufficient iodine intake. However, due to the relatively high risk of misclassification, further assessment of iodine status should follow.publishedVersio
Fatty acid reference intervals in red blood cells among pregnant women in Norway–Cross sectional data from the ‘Little in Norway’ cohort
There is a growing interest in determining fatty acid reference intervals from pregnancy cohort, especially considering the lack of reference values for pregnant women in the literature and the generalized misconception of equating reference intervals for nonpregnant women as equivalent to pregnant women. Seafood and supplements are important dietary sources for the omega-3 long-chain polyunsaturated fatty acids (ω-3 LCPUFA), such as eicosapentaenoic acid (EPA, 20:5ω-3), docosapentaenoic acid (DPA, 22:55ω-3), and docosahexaenoic acid (DHA, 22:6ω-3). Sufficient intake of EPA and DHA is vital during pregnancy for the development of the fetus, as well as for maintaining adequate levels for the mother. This study describes the fatty acid status and suggests reference values and cut-offs for fatty acids in red blood cells (RBC) from pregnant women (n = 247). An electronic food frequency questionnaire (e-FFQ) mapped the dietary habits of the participants, and gas chromatography was used to determine the fatty acid levels in RBC. The association between e-FFQ variables and fatty acid concentrations was established using a principal component analysis (PCA). Twenty-nine-point-one percent (29.1%) of the participants reported eating seafood as dinner according to the Norwegian recommendations, and they added in their diet as well a high percentage (76.9%) intake of ω-3 supplements. The concentration levels of fatty acids in RBC were in agreement with those reported in similar populations from different countries. The reference interval 2.5/97.5 percentiles for EPA, DPA, DHA were 0.23/2.12, 0.56/2.80, 3.76/10.12 in relative concentration units (%), and 5.99/51.25, 11.08/61.97, 64.25/218.08 in absolute concentration units (µg/g), respectively. The number of participants and their selection from all over Norway vouch for the representativeness of the study and the validity of the proposed reference values, and therefore, the study may be a useful tool when studying associations between fatty acid status and health outcome in future studies. To the best of our knowledge, this is the first PCA study reporting a direct association between ω-3 LCPUFA and intake of seafood and ω-3 supplements in a pregnancy cohort.publishedVersio
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